Here a perfect middle participle (feminine nominative singular) is glossed with a present active participle, the latter derived from the same root but with a different prefix. For different forms of the verb represented by the headword, see epsilon 2128 and epsilon 2431.
As Latte on Hesychius epsilon4333 (same headword, gloss kratou=sa) notes, the headword is surely quoted from Genesis 25.26 LXX: the hand of the newly-born Jacob grasps the heel of his brother Esau.